Email this article 
Anales del Jardín Botánico de Madrid, Vol 76, No 2 (2019)
Chemical and morphological characterization of Allium tuncelianum (Amaryllidaceae) and its antioxidant and anticholinesterase potentials
https://doi.org/10.3989/ajbm.2523
Songul Karakaya
Department of Pharmacognosy, Faculty of Pharmacy, Ataturk University, Turkey 
http://orcid.org/0000-0002-3268-721X
Gulnur Eksi
Department of Pharmaceutical Botany, Faculty of Pharmacy, Ankara University, Turkey http://orcid.org/0000-0002-6869-8703
Mehmet Koca
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ataturk University, Turkey http://orcid.org/0000-0002-1517-5925
Betul Demirci
Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Turkey http://orcid.org/0000-0003-2343-746X
Haluk Caglar Kaymak
Department of Horticulture, Faculty of Agriculture Ataturk University, Turkey http://orcid.org/0000-0002-0836-7654
Mehmet Emin Kaplan
Department of Pharmacognosy, Faculty of Pharmacy, Ataturk University, Turkey http://orcid.org/0000-0001-6833-4451
Ozkan Aksakal
Department of Biology, Faculty of Science, Ataturk University, Turkey http://orcid.org/0000-0003-0760-7502
Abstract
Keywords
References
Ağbaş B., Karakuş D., Adigüzel R., Keser S. & Demir E. 2013. Comparison of Total Antioxidant Properties and Dry Matter Content of Tunceli Garlic (Allium tuncelianum) and Normal Garlic (Allium sativum). Bilim ve Gençlik Dergisi 2: 50–62.
APGIII 2009. An update of the Angiosperm Phylogeny Group classification for the orders and the families of the flowering plants. Botanical journal of the Linnean Society 161: 105–121.
Chand R.N., Gopalan R.D. & Christi K. 2018. Evaluation of antioxidant properties in thirteen Fijian medicinal plants used in Alzheimer’s disease and related illness. Free Radicals and Antioxidants 8 (1): 11–17.
Chauhan N.B. 2003. Anti-Amyloidogenic effect of Allium sativum in Alzheimer’s transgenic model Tg2576. Journal of Herbal Pharmacotherapy 3: 95–107.
Dickson D.W. 1997. Neuropathological diagnosis of Alzheimer’s disease: A perspective from longitudinal clinicopathological studies. Neurobiology of Aging 18: 21–26.
Duman H., Ek?i G. & Özbek F. 2017. Two new species of Allium L. sect. Allium (Amaryllidaceae) from Turkey. Plant Systematics and Evolution 303: 1271–1291.
Ekşi G., Koyuncu M. & Özkan A.M.G. 2016. Allium ekimianum: a new species (Amaryllidaceae) from Turkey. PhytoKeys 62: 83–93.
Ellman G.L., Courtney K.D., Andresjr V. & Featherstone R.M. 1961. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology 7: 88–89.
Fritsch R.M. & Friesen N. 2002. Evolution, Domestication and Taxonomy. CABI, Wallingford.
Gibson G.E. & Huang H.M. 2005. Oxidative stress in Alzheimer’s disease. Neurobiology of Aging 26: 575–578.
Granato D., Shahidi F., Wrolstad R., Kilmartin P., Melton L.D., Hidalgo F.J., Miyashita K., Camp J., Alasalvar C., Ismail A.B., Elmore S., Birch G.G., Charalampopoulos D., Astley S.B., Pegg R., Zhou P. & Finglas P. 2018. Antioxidant activity, total phenolics and flavonoids contents: Should we ban in vitro screening methods? Food Chemistry 264: 471–475.
Karakaya S., Göger G., Kılıç C.S. & Demirci B. 2016. Composition of volatile oil of the aerial parts, flowers and roots of Ferulago blancheana Post. (Apiaceae) growing in Turkey and determination of their antimicrobial activities by bioautography method. Turkish Journal Of Pharmaceutical Sciences 13: 173–180.
Karakaya S., Koca M., Kılıc C.S. & Coskun M. 2018. Antioxidant and anticholinesterase activities of Ferulago syriaca Boiss. and F. isaurica Pe?men growing in Turkey. Medical Chemistry Research 27: 1843–1850.
Karakaya S., Koca M., Yılmaz S.V., Yıldırım K., Pınar N.M., Demirci B., Brestic M. & Sytar O. 2019. Molecular docking studies of coumarins isolated from extracts and essential oils of Zosima absinthifolia Link as potential inhibitors for Alzheimer’s Disease. Molecules 24 (4), E722: 1–18.
Kim M.J., Choi S., Kim H.K., Kim C.J., Hong B., Kim Y.J. & Shin D.H. 2007. Activation effects of Allium Tuberosum Rottl. on choline acetyltransferase. Bioscience, Biotechnology, and Biochemistry 71: 226–230.
Kiralan M., Rahimi A., Arslan N. & Bayrak A. 2013. Volatiles in an endemic Allium species: Allium tuncelianum by headspace solid phase microextraction. TEOP 16: 417–420.
Kollmann F., Özhatay N. & Koyuncu M. 1983. New Allium taxa from Turkey. Notes from the Royal Botanic Garden, Edinburgh 41 (2): 262.
López S., Bastida J., Viladomat F. & Codina C. 2002. Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts. Life Sciences 71: 2521–2529.
Manral A., Saini V., Meena P. & Tiwari M. 2015. Multifunctional novel diallyl disulfide (DADS) derivatives with b-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer’s disease. Bioorganic & Medicinal Chemistry 23: 6389–6403.
Mathew B. 1996. A review of Allium sect. Allium. Royal Botanic Gardens, Kew.
Mimica N.D., Bozin B., Sokovic M. & Simin N. 2004. Antimicrobial and antioxidant activities of Melissa officinalis L. (Lamiaceae) essential oil. Journal of Agricultural and Food Chemistry 52: 2485–2489.
Ng Y.P., Or T.C.T. & Ip N.Y. 2015. Plant alkaloids as drug leads for Alzheimer’s disease. Neurochemistry International 89: 260 e270.
Özhatay N. & Mathew B. 1995. New taxa and notes on the genus Allium (Alliaceae) in Turkey and Arabia. Kew Bulletin 50 (4): 723–731.
Özkan O., Gül S., Kart A., Çiçek B.A. & Kılıç K. 2013. In vitro antimutagenicity of Allium tuncelianum ethanol extract against induction of chromosome aberration by mutagenic agent mitomycine C. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 19: 259–262.
Ray B., Chauhan B.N. & Lahiri K.D. 2011. The “Aged Garlic Extract” (AGE) and one of its active ingredients S-Allyl-LCysteine (SAC) as potential preventive and therapeutic agents for Alzheimer’s disease (AD). Current Medicinal Chemistry 18: 3306–3313.
Resetár A., Freytag C., Kalydi F., Gonda S., M-Hamvas M., Ajtay K., Papp L. & Máthé C. 2017. Production and antioxidant capacity of tissue cultures from four Amaryllidaceae species. Acta Societatis Botanicorum Poloniae 86: 3525.
Şehitoğlu M.H., Karakan F.Y., Kizilkaya B., Öztopuz R.Ö. & Gülçin ?. 2018. Investigation of antioxidant properties and bioactive composition of Allium tuncelianum ((Kollman) Ozhatay, Matthew & Siraneci) and Allium sativum L. Journal of the Institute of Science and Technology 8: 213–221.
Sgarbossa A., Giacomazza D. & Carlo M. 2015. Ferulic Acid: A Hope for Alzheimer’s Disease Therapy from Plants. Nutrients 7: 5764–5782.
Sytar O., Bruckova K., Hunkova E., Zivcak M., Kiessoun K. & Brestic M. 2015. The application of muliplex flourimetric sensor for analysis flavonoids content in the medical herbs family Asteraceae, Lamiaceae, Rosaceae. Biological Research 48 (5): 2–9.
Takim K., Kutlu T., ?çen S., Demir N. 2016. Characterization of Tunceli mountain garlic essential oil component and determination effect on the antioxidant enzyme levels on rat renal tissue by dmba-induced. International Engineering, Science and Education Conference: 401–418.
Yerdelen K.O. & Tosun E. 2015. Synthesis, docking and biological evaluation of oxamide and fumaramide analogs as potential AChE and BuChE inhibitors. Medical Chemistry Research 24: 588–602.
Yumrutaş Ö., Demir S., Saygideğer Ö. & Doğan M. 2009. The in vitro antioxidant activity of Allium tuncelianum: An endemic. Journal of Applied Biological Sciences 3: 61–64.
Copyright (c) 2019 Consejo Superior de Investigaciones Científicas (CSIC)
This work is licensed under a Creative Commons Attribution 4.0 International License.
Contact us: anales@rjb.csic.es
Technical support: soporte.tecnico.revistas@csic.es